Figure 5
From: Orthopaedic applications of nanoparticle-based stem cell therapies
Superparamagnetic iron oxide nanoparticles bind to RGD receptors on the surface of osteoblasts. Confocal laser scanning microscopy images of MG63 bone-like cells after (a), (b) 4 hours and (c), (d) 24 hours incubation with RGD-coated 2.7 μm 'Flash red' fluorescent magnetic particles. The cytoplasm of viable cells is labelled with Calcein-AM (green). Reprinted from [85].