Figure 2From: Generation of disease-specific induced pluripotent stem cells from patients with different karyotypes of Down syndromeHuman induced pluripotent stem cells (iPSCs-DSs) lines express pluripotency markers. The iPSCs expressed alkaline phosphatase. As shown by the immunostaining results, the cells expressed pluripotency markers, including OCT4, SSEA4, TRA-1-60, and TRA-1-81. (A) DS/translocation-iPSC1. (B) DS/trisomy 21-iPSC2. (C) DS/trisomy 21-iPSC4. Nuclei are stained with DAPI (blue). Scale bars, 100 μm.Back to article page