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Figure 2 | Stem Cell Research & Therapy

Figure 2

From: The Aastrom experience

Figure 2

Changes in cell types during the culture process for ixmyelocel-T. (a) Fold change in cell phenotypes of the expanded and depleted cells in ixmyelocel-T. (b) Comparison of bone marrow mononuclear cells (BMMNCs) and ixmyelocel-T from a matched donor by flow cytometry. (c) Kinetics of expansion of CD90+ mesenchymal stem cells and CD14+Auto+ activated macrophages and overall loss of CD45 cells over time during ixmyelocel-T. (d) Immunofluorescence image of CD90 (red), CD14 (green), and nuclei (blue) at 600×. FACS, fluorescence-activated cell sorting.

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