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Figure 3 | Stem Cell Research & Therapy

Figure 3

From: The gene expression profiles of induced pluripotent stem cells from individuals with childhood cerebral adrenoleukodystrophy are consistent with proposed mechanisms of pathogenesis

Figure 3

Comparison of saturated very long chain fatty acid (sVLCFA) and plasmalogen levels in patient and healthy control fibroblasts and iPSCs. (A) Relative sVLCFA levels in patient and healthy control fibroblasts grown in fibroblast media or iPSC media, as represented by the C26:0/C22:0 LPC (lysophosphatidylcholine) ratio; (B) Relative sVLCFA levels in patient and healthy control iPSC clones grown in induced pluripotent stem cell (iPSC) media, again represented by the C26:0/C22:0 LPC ratio; (C) Relative plasmalogen level in patient and healthy control fibroblasts grown in fibroblast media and iPSC media, as represented by the total phosphatidyl ethanolamine (PE) plasmalogen/C22:0 lysophosphatidylcholine (LPC) ratio; (D) Relative plasmalogen in patient and healthy control iPSC clones grown in iPSC media, again represented by the total PE plasmalogen/C22:0 LPC ratio.

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Stem Cell Research & Therapy

ISSN: 1757-6512