Human bone marrow stem cell (hBM-MSC) cultures at P3, P6, P9, and P12. At all culture passages examined, hBM-MSCs displayed a fibroblast-like morphology. At P9, some extra- and intracellular debris (arrows) appeared and became more evident at P12. Images from donor 6 are shown by way of example. Bars, 100 μm.