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Table 2 Expression of extracellular matrix and adhesion molecules in LSK populations across different microenvironments and stages of development

From: Expression of migration-related genes is progressively upregulated in murine Lineage-Sca-1+c-Kit+ population from the fetal to adult stages of development

Gene

FL14.5

FL17.5

FBM17.7

Adult BM

Transmembrane molecules

Cd44

0.15

0.24

0.47

1

Entpd1

0.03

0.12

0.32

1

Itga4

0.38

0.49

0.62

1

Itgal

0.63

0.8

1.23

1

Itgam

0.3

0.43

0.72

1

Itgav

0.27

0.32

0.54

1

Itgb1

0.57

0.46

0.68

1

Itgb2

0.2

0.35

0.61

1

Itgb3

1.28

0.54

0.58

1

Pecam1

0.2

0.56

0.82

1

Sell

0.06

0.12

0.53

1

Selp

0.13

0.2

0.62

1

Sgce

0.1

0.39

0.68

1

Cell-cell adhesion molecules

Vcam1

0.08

0.27

0.36

1

Other adhesion molecules

Ctnna1

0.17

0.36

0.56

1

Ctnnb1

0.56

0.39

0.97

1

Emilin1

0.62

0.86

0.82

1

Lamb2

0.06

0.11

0.36

1

Lamc1

0.57

0.43

0.68

1

Collagens and extracellular matrix structural constituents

Col4a1

0.07

0.25

0.74

1

Col4a2

0.11

0.46

0.68

1

Extracellular matrix proteases

Adamts5

0.03

0.1

0.61

1

Mmp2

0.12

0.26

0.58

1

Extracellular matrix proteases

Timp2

0.08

0.22

0.58

1

Other extracellular matrix molecules

Ecm1

0.33

0.55

0.56

1

Tgfbi

0.07

0.22

0.45

1

Thbs1

4.26

1.02

0.43

1

Housekeeping gene

Hprt1

0.13

0.18

0.44

1

  1. Table demonstrates fold change values for samples in which gene expression was detected at all the points of study, compared to gene expression in adult bone marrow. Adult BM, four-week old adult bone marrow; FBM17.5, fetal bone marrow at Day 17.5 of gestation; FL14.5, fetal liver at Day 14.5 of gestation; FL17.5, fetal liver at Day 17.5 of gestation; LSK, Lineage- Sca-1+ c-Kit+.