Effect of PGCAP on mesenchymal stromal cell (MSC) and osteoprogenitor proliferation loaded on BM
. Not induced-MSCs (ni-MSCs) or osteogenic induced-MSCs (i-MSCs) loaded on BMA and BMF biomaterials at high cell seeding density (20 × 103 cells per biomaterial) were embedded or not in PGCAP and grown for 21 days. The number of cells was evaluated in each condition at days 10 and 21. The data are expressed as mean ± standard error of the mean. A statistically significant difference between individual conditions (without PGCAP) was revealed by analysis-of-variance test followed by Student Newman-Keuls. *P <0.05, **P <0.01. With PGCAP, similar tests revealed statistically significant difference between group comparing ni-MSCs and i-MSCs loaded on BMA ($*P <0.05) or group comparing ni-MSCs and i-MSCs at day 21 (#**P <0.01). PGCAP, platelet glue obtained from cryoprecipitation of apheresis platelet products.