Table 2 Some skeletal myogenesis-related genes are downregulated in MDSCs by myostatin genetic inactivation, whereas others remain unchanged

Spp1

Secreted phosphoprotein 1 (osteopontin)

70.8

20.3

Actc 1

α-Actin (cardiac)

39.9

6.5

Myo D1

Myogenic differentiation 1

17.5

2.7

Cadherin 15

Cadherin 15

8.7

1.7

Myf 5

Myogenic factor 5

4.2

2.7

Notch 2

Notch gene homolog 2

4.2

2.8

BMPR 2

Bone morphogenetic receptor 2

23.3

20.3

BMPR 1a

Bone morphogenetic receptor 1a

8.1

10.4

BMPR 1b

Bone morphogenetic receptor 1b

0.8

0.8

BMPR 4

Bone morphogenetic protein 4

2.7

2.7

IGF 1

Insulin-like growth factor 1

5.1

4.2

Jag 1

Jagged 1

2.8

3.4

Fzd 1

Frizzled homolog 1

2.7

2.8

Notch 1

Notch gene homolog 1

2.6

2.7

Notch 3

Notch gene homolog 3

2.8

2.6