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Figure 7 | Stem Cell Research & Therapy

Figure 7

From: Infusion of freshly isolated autologous bone marrow derived mononuclear cells prevents endotoxin-induced lung injury in an ex-vivo perfused swine model

Figure 7

Administration of freshly isolated whole bone marrow nuclear cells (BMC) altered the systemic inflammatory response to endotoxin. Compared to responses with buffy coat cells, sixty minutes after infusion of BMC, there was a significant suppression in endotoxin-induced increased systemic concentrations of pro-inflammatory cytokines (A) IL-1β and (B) TNF-α. There was no attenuation of endotoxin induced release of IL-6 by any of the cells administrated (C). (n = 6 in each group, **P <0.01, *P <0.05).

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Stem Cell Research & Therapy

ISSN: 1757-6512