Study outcome data. (A) Normalized peripheral blood (PB) concentration of CD34+ cells ([CD34+]). (B) Normalized PB concentration of CD34+CD38– cells ([CD34+CD38–]). (C) Absolute PB [CD34+]. (D) Absolute PB [CD34+CD38-]. n = 11 patients. Each donor is identified with the same color in all graphs. For (A) and (B), each dot represents an individual donor’s percentage change from their PB mean. A mixed model was used to estimate the quadratic trend in normalized values over time, assuming an autoregressive order 1 correlation structure. The three youngest donors have time point markers added to their lines. P values were obtained using paired t testing.