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Figure 6 | Stem Cell Research & Therapy

Figure 6

From: Simulated microgravity facilitates cell migration and neuroprotection after bone marrow stromal cell transplantation in spinal cord injury

Figure 6

Expression of apoptosis markers. Frozen sections were stained with apoptosis markers, Bax (B), Bcl-2 (C), and survivin (D), to examine the neurotrophic effects activated by grafted cells against apoptosis. The graph shows the positive cell percentage around SCI lesion in the frozen spinal cord sections (A) of each group (n = 6 per group). The number of Bax-positive cells was significantly decreased in group CL rats compared with the control group (P value < 0.01) and group 1G (P value < 0.05). Moreover, the number of survivin-positive cells was significantly increased in groups 1G and CL compared with the control (P value < 0.01; P value < 0.05). Bcl-2 expression was not statistically significantly different between groups. Data are expressed as mean ± SD. Scale bars, 300 μm (A), 100 μm (B, C, and D).

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