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Figure 2 | Stem Cell Research & Therapy

Figure 2

From: Monitoring neurodegeneration in diabetes using adult neural stem cells derived from the olfactory bulb

Figure 2

Differentiation abilities of adult NSCs derived from HPC and OB of diabetes rats. (A) Adult NSCs cultures derived from HPC and OB of diabetes rats. The adult NSCs isolated from HPC of control wild-type rats (WT) and diabetes (DB) rats are shown in left panels. The adult NSCs isolated from OB are shown in right panels. In vitro differentiated adult HPC- and OB neurons are also shown (Neuron). When the culture was exposed to neuron-differentiation conditions (RA + FSK + KCl), both HPC and OB cells extended neuritis. (B) Immunohistochemistory analysis (IHC) of the adult NSCs isolated from HPC (left) and OB (right) of control wild-type rats (WT) and diabetes (DB). IHC images using antibodies of Sox2 (red), Map2AB (green) are shown in the upper panels. IHC images using antibodies of GFAP (red), TUJ1 (green) were shown in lower panels.

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Stem Cell Research & Therapy

ISSN: 1757-6512