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Table 1 Functional grouping of osteogenic gene expression after 1 week of dynamic culture in vitro

From: Endothelial microvascular networks affect gene-expression profiles and osteogenic potential of tissue-engineered constructs

Gene Full name Fold change
Skeletal development
AHSG Alpha-2-HS-glycoprotein −3.7044
AMBN Ameloblastin −4.9367
AMELY Amelogenin −4.68
ENAM Enamelin −2.8164
STATH Statherin −9.6485
ALPL Alkaline phosphatase −3.6727
CALCR Calcitonin receptor −2.9072
DMP1 Dentin matrix acidic phosphoprotein 1 −3.9158
BMP3 Bone morphogenetic protein 3 −4.5315
BMP5 Bone morphogenetic protein 5 −4.9367
COL2A1 Collagen type II, alpha 1 −3.373
Cell growth and differentiation
IGF1R Insulin-like growth factor 1 receptor 3.5697
IGF2 Insulin-like growth factor 2 4.9403
TGFB3 Transforming growth factor beta 3 2.2567
IGF1 Insulin-like growth factor 1 2.964
BMP2 Bone morphogenetic protein 2 2.476
GDF10 Growth differentiation factor 10 2.2778
TWIST1 Twist homolog 1 2.1232
FLT1 Fms-related tyrosine kinase 1 −8.1751
Extracellular matrix molecules
MMP10 Matrix metallopeptidase 10 −5.3112
CSF2 Colony-stimulating factor 2 −4.9367
CSF3 Colony-stimulating factor 3 −4.9367
ITGAM Integrin alpha M −3.8558
COL14A1 Collagen type XIV, alpha 1 2.7336
CTSK Cathepsin K 2.019