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Figure 1 | Stem Cell Research & Therapy

Figure 1

From: 3′,4′-Dimethoxyflavone and valproic acid promotes the proliferation of human hematopoietic stem cells

Figure 1

3′4′-Dimethoxyflavone (DMF) and valproic acid (VPA) enhance the proportion of CD34+cells. The mean number and percentage of CD34+ cells was evaluated before (day 0) and after (day 7) the initiation of cytokine-induced cultures. (A) More mean CD34+ cells were found in the cultures with 3′4′-DMF and VPA compared with the control cultures after 7 days of amplification. (B): A higher percentage was found in the cultures with 3′4′-DMF and VPA compared with the control cultures after 7 days of amplification. (C) FACS analysis plots of CD34+ fractions from representative samples before (day 0) and after 7 days of amplification with cytokines alone (control), with 3′4′-DMF + cytokines and with VPA + cytokines. 3′4′-DMF (), VPA (), control at day 0() and control at day 7 (). The columns represent the mean ± SD values from three independent experiments.

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