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Figure 7 | Stem Cell Research & Therapy

Figure 7

From: Human conditionally immortalized neural stem cells improve locomotor function after spinal cord injury in the rat

Figure 7

The incorporation of host tissue elements into the graft 17 weeks after transplantation. SPC-01 cell survival and migration 17 weeks after transplantation was similar to that seen at 8 weeks. Transplanted cells were positive for GFAP (A and A1: higher magnification of A) and nestin (B and B1: higher magnification of B). At the same time, the grafts were infiltrated by endogenous cells and cell elements positive for NF200 (C and C1 and C2: higher magnification of C), Tau (D and D1), CGRP (E and E1), and NG2 (F), which suggests good communication with the host tissue. In the host nervous tissue adjacent to the transplants, endogenous cells positive for Olig2 (G) and MOSP (J) were found surrounding the implant.

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