Human CD34+ cells mobilized by granulocyte colony-stimulating factor ameliorate radiation-induced liver damage in mice

Table 1 Effect of G-CSF-mobilized CD34⁺ cells on murine liver function after irradiation

Mice	ALT (IU/L)				AST (IU/L)				ALB⁺/Y-chromosome⁺ cells
	0 d	3 d	7 d	21 d	0 d	3 d	7 d	21 d	14 d	21 d
G1	37.9 ± 7.2	418.3 ± 49.8^†	228.3 ± 32.7*	78.3 ± 5.7*	31.1 ± 6.9	398.3 ± 42.8^†	256.3 ± 36.8*	89.2 ± 6.4*	_	+^#
G2	36.4 ± 6.7	434.5 ± 53.8	378.6 ± 51.2	169.3 ± 34.7	29.8 ± 6.3	402.5 ± 46.5	381.2 ± 50.9	209.5 ± 38.4	_	_
G3	38.4 ± 7.1	40.9 ± 6.1	38.3 ± 6.8	42.3 ± 6.7	30.7 ± 6.5	31.7 ± 6.4	30.8 ± 6.9	31.1 ± 6.5	_	_

Data are means ± SD (n = 10). *P < 0.05 compared with the G2 mice; †P > 0.05 compared with the G2 mice. #Human ALB⁺/Y chromosome⁺ hepatocyte-like cells in the liver of G1 mice. G-CSF, granulocyte colony-stimulating factor; ALB, albumin; ALT, alanine aminotransferase aspartate; AST, aspartate aminotransferase.

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