Figure 1From: Conditionally immortalized stem cell lines from human spinal cord retain regional identity and generate functional V2a interneurons and motorneuronsCharacterization of human spinal cord neural stem cells conditionally immortalized with cMycER. (a) Clonal line SPC-01 expresses the neural stem cell markers Nestin and Sox2. (b) Cytogenetic analysis of SPC-01 after 60 population doublings (n = 20 metaphase cells), revealed a 46,XX normal female karyotype, demonstrating that conditional immortalization with cMycER and prolonged culture did not affect chromosomal stability in this line.Back to article page