Table 1 Log 2 -transformed data from Illumina beadchip expression analysis of SPC-01, SPC-04, and SPC-06 cell lines
| Â | Log2expression values (detection P value) | |||
|---|---|---|---|---|
Region | Gene ID | SPC-01 | SPC-04 | SPC-06 |
Roof plate | LMX1A | 5.55 (0.48) | 4.80 (0.30) | 4.16 (0.05) |
GDF7 | 5.94 (0.90) | 5.80 (0.89) | 5.56 (0.75) | |
Dorsal spinal cord | ATOH1 | 5.73 (0.68) | 5.85 (0.81) | 6.08 (0.91) |
OLIG3 | 6.12 (0.90) | 6.34 (0.96) | 6.06 (0.91) | |
GSX1 | 5.32 (0.36) | 5.09 (0.18) | 5.37 (0.73) | |
GSX2 | 4.39 (0.03) | 5.18 (0.37) | 5.40 (0.46) | |
PTF1A | 5.08 (0.18) | 5.00 (0.15) | 5.31 (0.34) | |
PAX7 | 9.13 (1.00) | 9.02 (1.00) | 9.27 (1.00) | |
Ventral spinal cord | DBX1 | 5.04 (0.51) | 4.84 (0.37) | 6.17 (0.94) |
NKX6.2 | 12.08 (1.00) | 11.50 (1.00) | 14.12 (1.00) | |
DBX2 | 5.64 (0.87) | 4.86 (0.26) | 5.85 (0.85) | |
NKX6.1 | 6.70 (0.98) | 7.29 (0.99*) | 7.05 (0.99) | |
IRX3 | 14.04 (1.00) | 13.77 (1.00) | 14.63 (1.00) | |
OLIG2 | 6.27 (0.95) | 8.25 (1.00) | 6.28 (0.93) | |
PAX6 | 10.07 (1.00) | 10.11 (1.00) | 10.33 (1.00) | |
NKX2.2 | 5.56 (0.51) | 5.53 (0.63) | 5.20 (0.30) | |
Floor plate | FOXA2 | 4.40 (0.09) | 4.80 (0.07) | 4.37 (0.02) |