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Figure 6 | Stem Cell Research & Therapy

Figure 6

From: Bone marrow-derived mesenchymal stem cells promote growth and angiogenesis of breast and prostate tumors

Figure 6

Bone marrow-derived mesenchymal stem cells promote tumor angiogenesis in vivo. Immunofluorescence analysis of blood vessel density in frozen sections from (a) 4T1 tumor or 4T1 combined with mouse bone marrow-derived mesenchymal stem cell (mBM-MSC) tumor by staining with anti-CD31 and (b) DU145 tumor or DU145 mixed with human bone marrow-derived mesenchymal stem cell (hBM-MSC) tumor by staining with anti-alpha smooth muscle actin (anti-α-SMA). DAPI (for nuclei staining) is blue; Arrows, blood vessels, Scale bar, 100 μm. Quantitative analysis of blood vessel density of (c) 4T1and (d) DU145 tumors using the ImageJ software (n = 6 per group; *P <0.05).

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