Figure 1
From: Topical administration of orbital fat-derived stem cells promotes corneal tissue regeneration
Orbital fat-derived stem cells (OFSCs) promoted corneal wound healing. In group A, a 70% central corneal defect was created. Topical (T) administration of OFSCs promoted corneal wound healing (A) and the area of residual epithelial defect under OFSCs was significantly lower than that of the PBS group on Day 2 (B). In group B, a 100% corneal injury with limbal involvement was created. The injured area significantly decreased with topical OFSC treatment. OFSCs promoted corneal re-epithelialization (C), and the injured area significantly decreased with topical OFSCs after the second day (D). (t-test, * P <0.05).