Figure 7
From: Topical administration of orbital fat-derived stem cells promotes corneal tissue regeneration
Diffuse stromal engraftment of OFSCs contributed to the corneal transparency. Seven days after multiple rounds of topical administration (A), OFSCs had not harmed the cornea. For the limbal-involved corneal injury, topical OFSCs (C) showed better therapeutic effects on wound healing and corneal transparency than topical PBS (B). Most quantum dot-labeled OFSCs were diffusely distributed in the stroma (D), while some of transplanted cells differentiated into p63-expressing cells at limbal epithelium (E) seven days after topical OFSC administration.