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Figure 1 | Stem Cell Research & Therapy

Figure 1

From: Human umbilical cord mesenchymal stem cell-derived neuron-like cells rescue memory deficits and reduce amyloid-beta deposition in an AβPP/PS1 transgenic mouse model

Figure 1

Neuron-like cell differentiation from HUMSCs by D609 induction. (A) Representative images of HUMSCs and HUMSC-NCs obtained by an inverted phase-contrast microscopy. Scale bar, 50 μm. (B) Immunocytochemistry staining for neuronal markers NSE (red) and MAP2 (red) in HUMSCs and HUMSC-NCs. Cells were fixed and stained with rabbit anti-human NSE IgG (1:200) or rabbit anti-human MAP2 IgG (1:200). Fluorescent dye-conjugated secondary antibody, goat anti-rabbit IgG-TRITC, was used to visualize the cells. Nuclei were stained with DAPI (blue). The images were captured with a camera system connected to a fluorescence microscope (Olympus 1x71S1F-3, Japan). Scale bar, 50 μm.

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Stem Cell Research & Therapy

ISSN: 1757-6512