Figure 1
Cell differentiation and stroke model. (A) Timeline of the differentiation process, stroke induction, and testing. Neural precursors were obtained approximately 2 weeks after seeding, and electrophysiology measurements were carried out every 7 days after re-plating. Transplantation was carried out at the neural precursor stage, 1 week after stroke induction. Adhesive removal training took place in the week before stroke. Testing was carried out 4 days after stroke and then 7, 14, 21, and 28 days after transplantation. BrdU injections were given daily beginning on the day of transplantation. (B) Representative blood flow measurements before and during the 7-minute ligation of the CCA, demonstrating a nearly complete blood flow reduction to the affected area.