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Figure 12 | Stem Cell Research & Therapy

Figure 12

From: Similar cellular migration patterns from niches in intervertebral disc and in knee-joint regions detected by in situ labeling: an experimental study in the New Zealand white rabbit

Figure 12

Images of Fe-labeled cells (blue) in investigated intervertebral disc (IVD) regions. Images from group 1 animals (2 to 3 weeks) and group 2 animals (5 to 6 weeks) after in situ Fe-labeling of cells in the niche region (SN). (A) Potential migration route (PMR) region. (B) The annulus fibrosus (AF). (C) Enlarged image of iron-labeled cell in AF indicated by square. (D) The nucleus pulposus (NP). (E) The germinal zone of the epiphyseal plate (EP). (F) Negative control; AF. Note the elongated migratory phenotype of cells in B and C. Enlarged images of Fe-labeled cells are enclosed in corners of images. Fe-labeled cells (blue) are indicated by grey arrows. Staining: russian blue reaction (Mallory method).

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