Figure 8

Selected images of BrdU⁺cells (yellow) in investigated KJ regions. (A) BrdU⁺ cell in niche region (SN) at day 14. (B) BrdU⁺ cells predominantly just outside niche region (SN) at day 28. (C) SNAI1⁺ cells (yellow) just outside niche region and in potential migration route (PMR) (note the larger fraction of SNAI1⁺ cells compared with the BrdU-labeled fraction of cells in Figure 6B). (D) Articular cartilage (AC) at day 14. (E) Articular cartilage (AC) at day 56. (F) SNAI1⁺ cells in AC. (G) Negative control, BrdU; niche region (SN). (H) Negative control, BrdU. AC. (I) SNAI1⁺ cells (yellow) in PMR. (J) BrdU⁺ cells in niche (SN) and PMR and BrdU⁺ cells in PMR. (Images J and K are merged from three separate photos). Nuclei stained with DAPI (blue).