Skip to main content

Table 2 Flow cytometry results of low- and high-passaged umbilical cord mesenchymal stem cells (UC MSCs)

From: Transplantation of umbilical cord-derived mesenchymal stem cells into the striata of R6/2 mice: behavioral and neuropathological analysis

  Passage 5 Passage 45
CD45 20.5 1.7
SCA1 26.9 30.1
SSEA4 10.9 55.4
MHC Class I 2.9 1.8
MHC Class II 10.8 1.5
  1. The number of cells positively expressing SCA1 remained relatively stable as passage number increased. A decrease in the hematopoietic stem cell marker CD45 was observed as cell passage increased. Also, an increase of expression of the stem cell marker SSEA4 between low- and high-passaged cells occurred. Expression of MHC Class I remained relatively stable between low- and high-passaged cells, but a decrease in MHC Class II was observed between low- and high-passaged cells, respectively. MHC, major histological complex; SSEA4, stage specific embryonic antigen 4.