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Figure 7 | Stem Cell Research & Therapy

Figure 7

From: Aldehyde dehydrogenase and ATP binding cassette transporter G2 (ABCG2) functional assays isolate different populations of prostate stem cells where ABCG2 function selects for cells with increased stem cell activity

Figure 7

Isolation of ALDHHi, ALDHLow, side population and non-side population cells from clinical human prostate specimen. Cells isolated from clinical human prostate specimen were stained with either DCV or ALDEFLUORâ„¢ reagent. The ALDHHi cells were detected in the higher fluorescent region (A). ALDHHi population was inhibited with DEAB resulting in no ALDHHi cell detection (B). Side population was gated based upon its absence in the presence of FTC, a specific inhibitor of ABCG2 (C and D).

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