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Figure 6 | Stem Cell Research & Therapy

Figure 6

From: Ixmyelocel-T, an expanded multicellular therapy, contains a unique population of M2-like macrophages

Figure 6

Ixmyelocel-T macrophages express M2 markers. Quantitative real-time PCR gene expression analysis of M1 and M2 macrophage markers within the ixmyelocel-T, M1, and M2 macrophages normalized to GAPDH (n ≥ 4). Relative expression of (A) PPARγ, (B) CD206, (C) CD163, (D) CD204, (E) SR-B1, (F) MERTK, (G) CCR7, (H) TNFα, (I) IL-1β, and (J) TGFβ in M1, M2, and IXT macrophages. Values are presented as mean ± SEM relative to IXT, *P <0.05,**P < 0.01, ***P < 0.001 vs M1, #P <0.05,##P < 0.01, ###P < 0.001 vs M2. PPAR-γ, peroxisome proliferator-activated receptor gamma; TGFβ, transforming growth factor beta.

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