Figure 4

Ixmyelocel-T promotes reverse cholesterol transport. In vivo cholesterol efflux was examined in SCID mice after intraperitoneal injections of either ³H-cholesterol-loaded J774 cells or ixmyelocel-T. (A) Plasma ³H-cholesterol levels after 24 and 48 hours, (B)³H-tracer found in the liver, and (C)³H-tracer found in the feces after 48 hours (n ≥ 3 per group). Values are presented as mean ± SEM relative to control, ^*P < 0.05 versus J774. SCID, severe combined immunodeficient; SEM, standard error of the mean.