Figure 2From: Design considerations for an integrated microphysiological muscle tissue for drug and tissue toxicity testingMicrophysiological system with engineered human muscle. (a) Schematic of the perfusion system showing the relation among the ferrogel pump, human tissue-engineered blood vessel (TEBV), muscle tissue and other microphysical tissue or organ systems. Q, flow rate; QM, flow rate to engineered muscle; QT, flow rate to other microphysiological tissues. (b1) Aligned three-dimensional human skeletal muscle tissue showing actin striations indicative of sarcomeres. (b2) Human endothelial cells covering a monolayer of differentiated human skeletal muscle in two-dimensional cultures. (c1) Schematic of fluidic magnetically activated ferrogel valve. (c2) Effect of magnetic field on magnetically activated ferrogel. (c3) Velocity of microparticles at 1 Hz and 5 μl/minute in fluidic channel.Back to article page