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Figure 9 | Stem Cell Research & Therapy

Figure 9

From: Apoptotic adipose-derived mesenchymal stem cell therapy protects against lung and kidney injury in sepsis syndrome caused by cecal ligation puncture in rats

Figure 9

Histopathological scoring of kidney injury at 72 hours after the CLP procedure. A to D) H & E stain (400x) showing a significantly higher degree of loss of brush border in renal tubules (yellow arrows), tubular necrosis (green asterisk) and dilatation of Bowman’s capsule (blue arrows) in the CLP group than in the other groups. E) * versus other groups with different symbols (*, †, ‡, §), P <0.0001. All statistical analyses using one-way ANOVA, followed by the Bonferroni multiple comparison post hoc test (n = 8). Symbols (*, †, ‡, §) indicate significance (at 0.05 level). Scale bars in the right lower corner represent 20 μm. SC, sham control; CLP, cecal ligation and puncture; H-ADMSC, healthy adipose-derived mesenchymal stem cell; A-ADMSC, apoptotic adipose-derived mesenchymal stem cell. ANOVA, analysis of variance.

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