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Figure 3 | Stem Cell Research & Therapy

Figure 3

From: Quantitative proteomic analysis of sphere-forming stem-like oral cancer cells

Figure 3

Quantitative proteomic analysis of CSC-like and non-CSC UM1 cancer cells using tandem mass tagging (TMT) and two-dimensional LC-MS/MS. Ratios of 127 to 126 represent the relative levels of proteins between non-CSC (TMT-127) and CSC-like (TMT-126) UM1 cells. (A) depicts the corresponding number of protein IDs with ≥1 matched peptide (n = 4,397), ≥2 matched peptides (n = 1,026), ≥1 matched and TMT-labeled peptide (n = 936), or ≥2 matched and TMT-labeled peptides (n = 425). (B) illustrates the TMT-127/TMT-126 ratios for 936 proteins with ≥1 matched and TMT-labeled peptide. (C) illustrates the TMT-127/TMT-126 ratios for 425 proteins with ≥2 matched and TMT-labeled peptides. CSC, cancer stem cells; LC-MS/MS, liquid chromatography-tandem mass spectroscopy.

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