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Table 1 Stereological analysis of wounds in diabetic animals

From: Autologous circulating angiogenic cells treated with osteopontin and delivered via a collagen scaffold enhance wound healing in the alloxan-induced diabetic rabbit ear ulcer model

Parameter CACs (OPN) + Collagen CACs + Collagen Collagen Untreated
Wound volume (mm3) 13.2 ± 5.1* 14.1 ± 3.5 17.4 ± 3.6#* 12.03 ± 3.69
Total volume of inflammatory cells (mm3) 2.37 ± 0.97# 3.01 ± 1.16# 3.21 ± 0.91# 1.39 ± 0.5
Surface density of blood vessels in wound (mm-1) 22.4 ± 9.3# 21.6 ± 4.34# 25.6 ± 5.8# 11.1 ± 5
Surface area of blood vessels (mm2) 306.3 ± 178 330.5 ± 20# 442 ± 112# 146 ± 116
Length density of blood vessels in wound (mm-2) 6,212 ± 1,424# 6,534 ± 1,589# 7,575 ± 1,610# 4,116 ± 1093
Total length of blood vessels in wound (mm) 81,678 ± 35,117 90,490 ± 26,997# 131,220 ± 34,187# 49,337 ± 51595
Radial diffusion distance (μm) 7.29 ± 0.9# 7.16 ± 0.1# 6.56 ± 0.6# 9.05 ± 0.15
Vessel diameter (μm) 1.8 ± 0.47# 1.76 ± 0.46 1.74 ± 0.3 1.35 ± 0.38
  1. Stereology analyzed by ANOVA followed by Fisher’s pairwise comparison, mean ± standard deviation, n = 8, *P <0.05 compared to * in the same row, #P <0.05 compared to untreated wound.