Skip to main content
Figure 2 | Stem Cell Research & Therapy

Figure 2

From: Human umbilical cord tissue-derived mesenchymal stromal cells attenuate remodeling after myocardial infarction by proangiogenic, antiapoptotic, and endogenous cell-activation mechanisms

Figure 2

Transplantation of UCX® into MI hearts increased capillary density and decreased apoptosis. Representative images of vehicle–injected ( n = 6, A and D) and UCX®-transplanted hearts ( n = 5, B and E) stained for CD31 (A and B, red) and for cellular apoptosis (D and E, bright green). (C) CD31-expressing cells were more abundant within the infarcted LV wall of UCX®-transplanted hearts when compared with the vehicle control group. (F) UCX®-transplanted hearts showed fewer apoptotic cells in the apical region when compared with vehicle-injected hearts, suggesting an anti-apoptotic protective effect by the UCX®. Green filter in A and B denotes tissue autofluorescence. *P < 0.05; scale bars = 100 μm.

Back to article page

Stem Cell Research & Therapy

ISSN: 1757-6512