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Figure 3 | Stem Cell Research & Therapy

Figure 3

From: Cell distribution after intracoronary bone marrow stem cell delivery in damaged and undamaged myocardium: implications for clinical trials

Figure 3

99mTc-BM-MNC biodistribution after intracoronary injection in animals with or without myocardial infarction. The percentage of radioactivity in organs was calculated by dividing organ radioactivity with the total injected quantity after radioactive decay correction, one hour after injection. A: Comparison between two radioactivity quantification methods in the same animal: values from measured radioactivity in isolated organs (x-axis), and values from regions of interest drawn in the scintigraphic whole body acquisition images (y-axis). B: Radioactivity quantification in animals with (MI) or without (no MI) myocardial infarction, after intracoronary injection of Isolink™/99mTc only or 99mTc-BM-MNCs. Bars indicate mean and SD (P > 0.05, not significant). C: Individual quantities of radioactivity in pigs with or without MI (P > 0.05, not significant). Radioactivity was quantified in 1 g myocardium inside the infarcted area, in the left and right ventricles distant from infarcted area, and in the left and right auricles.

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