Figure 9From: Extracellular matrix remodeling following myocardial infarction influences the therapeutic potential of mesenchymal stem cellsMSC-conditioned media promotes cardiomyocyte survival after oxidative stress. The conditioned-media samples derived from MSCs cultured in the presence of matrix have a greater ability to rescue oxidatively stressed cardiomyocytes as compared with those cells cultured on TCP (P < 0.05) or media that has not been conditioned by MSCs (P < 0.05). Conditioned media samples from cells cultured on 4 week matrix have a greater ability to prevent cardiomyocyte death as compared with cells cultured on healthy matrix (P < 0.1) (n = 6).Back to article page