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Figure 1 | Stem Cell Research & Therapy

Figure 1

From: Glutathione S-transferase Mu 2-transduced mesenchymal stem cells ameliorated anti-glomerular basement membrane antibody-induced glomerulonephritis by inhibiting oxidation and inflammation

Figure 1

Kidney gene expression profiling of five mice strains in an anti-glomerular basement membrane antibody-induced glomerulonephritis (anti-GBM-GN) mouse model. (A) A group of oxidative stress-related genes that were differentially expressed between anti-GBM-GN-resistant mouse strains (B6 and BALB/c) and anti-GBM-GN-sensitive strains (DBA1, 129/svj, and NZW). The GSTM2 gene was up-regulated in anti-GBM-GN-resistant strains compared with anti-GBM-GN-sensitive strains. (B) Expression of glutathione S-transferase Mu 2 (GSTM2) in different mouse strains was confirmed by reverse transcription quantitative PCR.

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Stem Cell Research & Therapy

ISSN: 1757-6512