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Figure 2 | Stem Cell Research & Therapy

Figure 2

From: Differential fate and functional outcome of lithium chloride primed adult neural progenitor cell transplants in a rat model of Huntington disease

Figure 2

In vitro priming of SVZ-derived adult neural progenitor cells with lithium chloride reduces gliogenesis 12 weeks after transplantation. Representative confocal micrographs in low power and in high power with orthogonal projections of BrdU-labeled lithium chloride-primed adult neural progenitor cells co-expressing (a through d) the immature neural progenitor cell marker SOX-2, (f through i) the astrocytic marker GFAP, and (k through n) the mature neuronal marker NeuN. Graphs comparing the proportion of transplanted BrdU-labeled cells co-expressing (e) SOX2, (j) GFAP, or (o) NeuN labeling 12 weeks after transplantation. Scale bar, 40 μm (a, f, and k) and 20 μm (B-D, G-I, L-N). *P < 0.05; ***P < 0.001.

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