|
Group
|
Baseline
|
1 W
|
2 W
|
4 W
|
|---|
|
EF (%)
| | | | |
|
Control
|
91.61 ± 5.79
|
32.16 ± 5.05
|
30.72 ± 3.19
|
25.87 ± 5.58
|
|
MSCs
|
90.51 ± 6.70
|
34.97 ± 5.87
|
32.23 ± 8.52
|
27.26 ± 6.38
|
|
HIF-1α-MSCs
|
91.07 ± 6.23
|
35.31 ± 7.46
|
33.10 ± 8.12
|
29.23 ± 8.63
|
|
HIF-1α
|
92.12 ± 5.54
|
35.57 ± 6.82
|
32.94 ± 7.38
|
30.99 ± 9.00
|
|
HIF-1α + MSCs
|
91.95 ± 6.71
|
37.18 ± 8.07
|
38.25 ± 5.72
|
40.96 ± 8.91&★△*
|
|
FS (%)
| | | | |
|
Control
|
64.71 ± 2.28
|
16.48 ± 2.64
|
15.17 ± 1.80
|
12.60 ± 2.61
|
|
MSCs
|
63.64 ± 2.21
|
17.42 ± 3.20
|
16.51 ± 5.38
|
13.38 ± 4.52
|
|
HIF-1α-MSCs
|
64.07 ± 2.89
|
17.57 ± 4.09
|
16.64 ± 4.17
|
14.35 ± 4.07
|
|
HIF-1α
|
64.92 ± 2.94
|
17.86 ± 3.85
|
16.53 ± 3.91
|
15.62 ± 4.05
|
|
HIF-1α + MSCs
|
64.45 ± 3.15
|
18.88 ± 5.69
|
19.42 ± 3.27
|
21.04 ± 4.10&★△*
|
- &P <0.05 vs. HIF-1α group, ★P <0.05 vs. HIF-1α-MSCs group, △P <0.01 vs. MSCs group, *P <0.01 vs. Control group. EF, ejection fraction; FS, fractional shortening; HIF-1α, hypoxia-inducible factor-1α; MSCs, mesenchymal stem cells.
