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Table 2 Assessment of LV function (EF and FS) by echocardiography

From: Myocardial transfection of hypoxia-inducible factor-1α and co-transplantation of mesenchymal stem cells enhance cardiac repair in rats with experimental myocardial infarction

Group

Baseline

1 W

2 W

4 W

EF (%)

    

Control

91.61 ± 5.79

32.16 ± 5.05

30.72 ± 3.19

25.87 ± 5.58

MSCs

90.51 ± 6.70

34.97 ± 5.87

32.23 ± 8.52

27.26 ± 6.38

HIF-1α-MSCs

91.07 ± 6.23

35.31 ± 7.46

33.10 ± 8.12

29.23 ± 8.63

HIF-1α

92.12 ± 5.54

35.57 ± 6.82

32.94 ± 7.38

30.99 ± 9.00

HIF-1α + MSCs

91.95 ± 6.71

37.18 ± 8.07

38.25 ± 5.72

40.96 ± 8.91&*

FS (%)

    

Control

64.71 ± 2.28

16.48 ± 2.64

15.17 ± 1.80

12.60 ± 2.61

MSCs

63.64 ± 2.21

17.42 ± 3.20

16.51 ± 5.38

13.38 ± 4.52

HIF-1α-MSCs

64.07 ± 2.89

17.57 ± 4.09

16.64 ± 4.17

14.35 ± 4.07

HIF-1α

64.92 ± 2.94

17.86 ± 3.85

16.53 ± 3.91

15.62 ± 4.05

HIF-1α + MSCs

64.45 ± 3.15

18.88 ± 5.69

19.42 ± 3.27

21.04 ± 4.10&*

  1. &P <0.05 vs. HIF-1α group, P <0.05 vs. HIF-1α-MSCs group, P <0.01 vs. MSCs group, *P <0.01 vs. Control group. EF, ejection fraction; FS, fractional shortening; HIF-1α, hypoxia-inducible factor-1α; MSCs, mesenchymal stem cells.