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Table 2 Assessment of LV function (EF and FS) by echocardiography

From: Myocardial transfection of hypoxia-inducible factor-1α and co-transplantation of mesenchymal stem cells enhance cardiac repair in rats with experimental myocardial infarction

Group Baseline 1 W 2 W 4 W
EF (%)     
Control 91.61 ± 5.79 32.16 ± 5.05 30.72 ± 3.19 25.87 ± 5.58
MSCs 90.51 ± 6.70 34.97 ± 5.87 32.23 ± 8.52 27.26 ± 6.38
HIF-1α-MSCs 91.07 ± 6.23 35.31 ± 7.46 33.10 ± 8.12 29.23 ± 8.63
HIF-1α 92.12 ± 5.54 35.57 ± 6.82 32.94 ± 7.38 30.99 ± 9.00
HIF-1α + MSCs 91.95 ± 6.71 37.18 ± 8.07 38.25 ± 5.72 40.96 ± 8.91&*
FS (%)     
Control 64.71 ± 2.28 16.48 ± 2.64 15.17 ± 1.80 12.60 ± 2.61
MSCs 63.64 ± 2.21 17.42 ± 3.20 16.51 ± 5.38 13.38 ± 4.52
HIF-1α-MSCs 64.07 ± 2.89 17.57 ± 4.09 16.64 ± 4.17 14.35 ± 4.07
HIF-1α 64.92 ± 2.94 17.86 ± 3.85 16.53 ± 3.91 15.62 ± 4.05
HIF-1α + MSCs 64.45 ± 3.15 18.88 ± 5.69 19.42 ± 3.27 21.04 ± 4.10&*
  1. &P <0.05 vs. HIF-1α group, P <0.05 vs. HIF-1α-MSCs group, P <0.01 vs. MSCs group, *P <0.01 vs. Control group. EF, ejection fraction; FS, fractional shortening; HIF-1α, hypoxia-inducible factor-1α; MSCs, mesenchymal stem cells.