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Table 2 SB623-to-parental MSC ratios of mRNA expression levels

From: Comparison of the neuropoietic activity of gene-modified versus parental mesenchymal stromal cells and the identification of soluble and extracellular matrix-related neuropoietic mediators

 

FGF1

FGF2

FGFR1

FGFR2

BMP2

BMP4

BMP6

HB-EGF

EGF

HGF

GAP

SB623/MSC expression

1.3a

1.7a

0.7a

0.2a

ND

3.6a

1.6

0.9

1.5

0.7

 

SD

0.27

0.47

0.13

0.08

ND

2.27

1.19

0.47

0.75

0.72

 

Cp

28

26.5

26

27

35

30

33

29

30.5

31

21

  1. Values represent averaged ratios obtained from qRT-PCR data on eight pairs of MSCs and SB623 for all factors, except for BMP2 and BMP6, where data from six MSC/SB623 pairs were used. SD, standard deviation; Cp, crossing point (threshold PCR cycle at which the signal becomes measurable), aP < 0.05.