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Figure 2 | Stem Cell Research & Therapy

Figure 2

From: Microvesicles derived from human Wharton’s Jelly mesenchymal stromal cells ameliorate renal ischemia-reperfusion injury in rats by suppressing CX3CL1

Figure 2

Effects of hWJMSC-MV administration on the proliferation and apoptosis of tubular epithelium cells. (A) Representative images of Ki67 and TUNEL immunostaining in the injured kidneys at 48 h after reperfusion treated with hWJMSC-MVs (magnification 200×, Scale bar = 50 um). (B) Quantification of TUNEL-positive tubular epithelium cells in the kidney sections at different time points after reperfusion with hWJMSC-MVs. (n = 6,*P <0.05, sham versus vehicle; #P <0.05, MVs versus vehicle, **P <0.05, sham versus MVs). (C) Quantification of Ki67-positive tubular epithelium cells in the kidney sections at different time points after reperfusion with hWJMSC-MVs. (n = 6, *P <0.05, sham versus vehicle; #P <0.05, MVs versus vehicle, **P <0.05, sham versus MVs).

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