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Figure 4 | Stem Cell Research & Therapy

Figure 4

From: Microvesicles derived from human Wharton’s Jelly mesenchymal stromal cells ameliorate renal ischemia-reperfusion injury in rats by suppressing CX3CL1

Figure 4

hWJMSC-MVs reduce the α-smooth muscle actin (α-SMA) expression in kidney tissues. (A) Representative micrographs illustrating α-smooth muscle actin (α-SMA) expression in kidney tissues, In comparison with MVs group, the vehicle group exhibited stronger positive staining for α-SMA in kidney tissue sections at two weeks (the original magnification is 400×, Scale bar = 50 um). (B, C) α-SMA expression in kidney tissues was measured by Western blot analysis, and MVs dramatically reduce the α-SMA expression, all quantitative data are shown as mean ± SD of three experimental conditions (n = 3, *P <0.05, sham versus vehicle; #P <0.05, MVs versus vehicle).

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