The effects of microRNAs on human neural stem cell differentiation in two- and three-dimensional cultures

Stevanato, Lara; Sinden, John D

doi:10.1186/scrt437

Stem Cell Research & Therapy

Table 1 Statistical analysis performed on miRNA PCR arrays

From: The effects of microRNAs on human neural stem cell differentiation in two- and three-dimensional cultures

	P-values (compared with control group)				P values (compared with 2D versus 3D)
Mature ID	2D (1W)	3D (1W)	2D (3W)	3D (3W)	(1W)	(3W)	Regulation
hsa-miR-302a-3p	✶	✶✶✶	✶✶✶	✶✶✶	✶✶✶	✶✶	Down
hsa-miR-10a-5p	NS	NS	✶✶✶	✶✶✶	✶✶✶	✶
hsa-miR-10b-5p	NS	✶	✶✶✶	✶✶✶	NS	NS
hsa-miR-96-5p	✶✶✶	✶✶✶	✶✶✶	✶✶✶	✶✶✶	✶✶
hsa-miR-183-5p	✶✶✶	✶✶✶✶	✶✶✶	✶✶✶	✶✶✶	✶✶✶
hsa-miR-182-5p	✶✶✶	✶✶✶	✶✶✶	✶✶✶	✶	NS
hsa-miR-7-5p	✶✶✶	✶✶✶	✶✶✶	✶✶✶	✶✶	NS
hsa-miR-17-5p	✶✶✶	✶✶✶	✶✶✶	✶✶✶	✶✶✶	✶✶✶
hsa-miR-18a-5p	✶✶✶	✶✶✶	✶✶✶	✶✶✶	✶✶✶	✶✶✶
hsa-miR-20a-5p	✶✶	✶✶✶	✶✶✶	✶✶✶	✶✶✶	✶✶✶
hsa-miR-20b-5p	✶✶✶	✶✶✶	✶✶✶	✶✶✶	✶	✶✶✶
hsa-miR-93-5p	✶✶✶	✶✶✶	✶✶✶	✶✶✶	✶✶✶	✶✶
hsa-miR-106b-5p	✶✶✶	✶✶✶	✶✶✶	✶✶✶	✶✶✶	✶✶
hsa-miR-15a-5p	NS	NS	✶✶✶	✶	NS	NS
hsa-miR-15b-5p	NS	NS	✶✶✶	✶✶✶	NS	NS
hsa-miR-16-5p	NS	NS	✶✶✶	✶✶	NS	NS
hsa-miR-195-5p	NS	✶	✶✶✶	✶✶	NS	NS
hsa-miR-21-5p	✶	NS	NS	✶✶	✶✶✶	✶✶
hsa-miR-33a-5p	NS	NS	✶✶✶	✶✶	NS	NS
hsa-miR-128	NS	NS	✶	✶	NS	NS
hsa-miR-424-5p	NS	NS	✶✶	✶✶✶	✶✶✶	NS
hsa-miR-130a-3p	NS	✶✶	✶✶✶	✶	NS	NS
hsa-miR-345	✶	✶✶✶	✶✶✶	✶✶✶	NS	NS
hsa-let-7b	✶✶✶	✶✶✶	✶✶✶	✶✶✶	✶✶✶	NS	Up
hsa-let-7c	✶✶✶	✶✶✶	✶✶✶	✶✶✶	✶✶✶	✶✶✶
hsa-miR-146b-5p	✶✶✶	✶	✶✶✶	✶✶✶	✶✶✶	NS
hsa-miR-23b	✶✶✶	✶✶✶	✶✶✶	✶✶✶	✶✶✶	NS
hsa-miR-99a	✶✶✶	✶✶✶	✶✶✶	✶	✶✶✶	NS

Data were analyzed with Student t test, ✶ P < 0.05, ✶✶P < 0.001, ✶✶✶ P < 0.005, and nonsignificant (NS).

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ISSN: 1757-6512

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