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Figure 3 | Stem Cell Research & Therapy

Figure 3

From: RETRACTED ARTICLE: Umbilical cord tissue-derived mesenchymal stem cells induce apoptosis in PC-3 prostate cancer cells through activation of JNK and downregulation of PI3K/AKT signaling

Figure 3

Effect of JNK SP60015 on PARP, cleaved caspase 3, cleaved caspase 9, and p-JNK induced by hUCMSCs in PC-3 cells. (A) Effect of hUCMSCs on PARP, Bax, and cleaved caspase 9 in PC-3 cells. (B) Effect of JNK SP60015 on PARP, cleaved caspase 3, cleaved caspase 9, and p-JNK induced by hUCMSCs in PC-3 cells was detected in immunoblotting assay. (C) In the same condition as in (B), expression levels of cleaved caspase, cleaved PARP, and p-JNK were analyzed by immunofluorescence assay. Each primary antibody was diluted 1/300. Light green indicates cleaved caspase 3, cleaved PARP, and p-JNK. DAPI (Blue).

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