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Figure 4 | Stem Cell Research & Therapy

Figure 4

From: RETRACTED ARTICLE: Umbilical cord tissue-derived mesenchymal stem cells induce apoptosis in PC-3 prostate cancer cells through activation of JNK and downregulation of PI3K/AKT signaling

Figure 4

Effect of hUCMSCs on survival genes and JNK in PC-3 cells. PC-3 cells were cultured for 24 hours alone or in the presence of hUCMSCs at the ratio (hUCMSCs:PC-3, 1:3). Cells lysates were immunoblotted with PI3K, p-AKT, AKT, p-ERK, ERK, p-JNK, JNK and PARP, Bax, cleaved caspase 9, and β-actin antibodies. (A) Effect of hUCMSCs on PI3K, AKT, ERK, and JNK in PC-3 cells. (B) Effect of hUCMSCs on Bcl-2, Bcl-xL, survivin, cIAP-1, and β-actin in PC-3 cells.

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Stem Cell Research & Therapy

ISSN: 1757-6512