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Table 2 Histologic scoring

From: Fetal derived embryonic-like stem cells improve healing in a large animal flexor tendonitis model

Tendon parameter Fetal-derived embryonic-like stem cell treated tendon Placebo control treated tendon Two-tailed P
Cell shape 1.0 (0.9 to 1.3) 2.0 (1.8 to 2.3)* <0.0001
Cell density 1.0 (2.0 to 2.0) 2.75 (2.3 to 3.0)* 0.0002
Free hemorrhage 1.0 (0.9 to 1.7) 1.75 (1.1 to 2.4) 0.1
Neo-vascularization 2.0 (1.4 to 2.2) 2.0 (1.2 to 2.3) 0.7
Perivascular cuffing 1.5 (1.1 to 2.0) 1.0 (0.83 to 1.4) 0.1
Collagen linearity 2.0 (1.3 to 2.1) 2.75 (2.4 to 3.0)* <0.0001
Collagen uniformity 2.0 (1.4 to 2.1) 3.0 (2.8 to 3.1)* <0.0001
Polarized crimping 1.5 (1.2 to 2.1) 3.0 (2.7 to 3.3)* <0.0001
Epitenon thickening 2.3 (2.0 to 2.6) 3.0 (2.6 to 3.5)* 0.0009
Cumulative Score 15.4 (12.6 to 17.8) 20.8 (19.0 to 23.0)* <0.0001
  1. Histologic scores for fetal-derived embryonic-like stem cell treated tendon and placebo control treated tendon reported as median (95% confidence interval). Significant differences between treatment groups are marked by an asterisk (two-tailed P < 0.05) and the two-tailed P- values are listed.