Figure 5From: MicroRNA-363 negatively regulates the left ventricular determining transcription factor HAND1 in human embryonic stem cell-derived cardiomyocytesmiR-363 targeting of the 3′UTRs of HAND1 and HAND2 . Reduced luciferase activity in HEK293 (A) and hESCs (B) overexpresses pre-miR-363 and HAND1 or HAND2 reporters. Plasmids expressing firefly luciferase without 3′UTRs were used as controls. Data shown are mean ± SEM (n = 3); *P < 0.05.Back to article page