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Figure 7 | Stem Cell Research & Therapy

Figure 7

From: MicroRNA-363 negatively regulates the left ventricular determining transcription factor HAND1 in human embryonic stem cell-derived cardiomyocytes

Figure 7

miR-363 selectively inhibits HAND1 expression. hESCs pretreated with BMP4 were transfected with pre-miR-363. Relative expressions of cardiac-specific transcription factors were analyzed by qPCR. HAND1 mRNA levels decreased with addition of pre-miR-363, relative to HAND2 and other transcription factors. Data shown are mean ± SEM (n = 3); *P < 0.05.

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