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Figure 4 | Stem Cell Research & Therapy

Figure 4

From: Osteoarthritic cartilage explants affect extracellular matrix production and composition in cocultured bone marrow-derived mesenchymal stem cells and articular chondrocytes

Figure 4

Immunofluorescence staining of collagens. Representative immunofluorescence staining images of collagens (A) I, (B) II, (C) III, and (D) X detected on cryosections after 28 days of culture. Bone marrow-derived stem cells (BMSCs), mixed cultures (BMSCs and chondrocytes in a ratio of 1:1), or chondrocytes were monocultured (F) or co-/tri-cultured with osteoarthritis cartilage (FC). Nuclei were stained with 4′,6-diamidino-2-phenylindole (DAPI) (blue color). Scale bar is 100 μm. N = 5.

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