Figure 6

Gene expression of inflammatory mediators in the heart. Heart samples of uninfected or chagasic mice treated with saline or cardiac mesenchymal stem cells (CMSCs) were removed 2 months after therapy and analyzed by quantitative real-time reverse transcription polymerase chain reaction for the expression of interleukin-6 (IL-6) (A), tumor necrosis factor-alpha (TNF-α) (B) (*P <0.05 versus saline and ***P <0.001 versus non-infected), transforming growth factor-beta (TGF-β) (C) (*P <0.05 versus saline and **P <0.01 versus non-infected), interferon-gamma (IFN-γ) (D) (*P <0.05 versus saline), cyclooxigenase 2 (COX-2) (E), and IL-10 (F) (**P <0.01 versus non-infected).